John Gordan, MD PhD
john.gordan (at) ucsf.edu
I am a physician scientist, with research training in cancer biology and chemical biology. My PhD mentor was Celeste Simon (University of Pennsylvania) and postdoctoral mentor Kevan Shokat (UCSF). My clinical practice focuses on the treatment of primary liver cancers, and my research goal is to develop mechanistic insights into these tumors to identify new therapeutic targets. The Gordan lab is a young and dynamic group of scientists based in Quantitative Biosciences Institute at UCSF Mission Bay. I am very happy to have an exciting, inclusive and fun environment in the lab, with synergy between basic and translational projects. When I’m not in the lab or the clinic, I am usually trying to convince my family and dog to go hiking with me.
Nia Adeniji, MD MEng
Hematology/Oncology Fellow
nia.adeniji (at) ucsf.edu
My name is Nia Adeniji, and I am currently a second-year oncology fellow at UCSF in the Gordan and Huang Labs. I received my undergraduate degree from MIT, where I studied biological chemical engineering before receiving a Masters in Bioengineering. I then took my process-oriented training and mindset with me to Genentech, where I developed antibody-drug conjugates in the Early- and Late-Stage Pharmaceutical Development departments for 6 years. Because I found myself drawn to the oncology clinical trials that I was supporting, and the patient outcomes on those trials, I decided to pursue a medical degree, which I obtained from Stanford University. There I discovered both a clinical and investigational research interest in hepatobiliary oncology.
My research interest is in understanding the ways in which the tumor immune microenvironment (TIME) of hepatocellular carcinoma (HCC) drives tumor development, progression, recurrence and treatment response. My ultimate goal is to provide a tissue-specific algorithm that can better direct clinical management for the large number of intermediate stage patients with HCC. I am currently looking to identify the unique immune compartments and signatures that influence HCC recurrence risk using multiplex imaging and spatial transcriptomics.
Tim Kellett, PhD
Postdoctoral Research Fellow
timothy.kellett (at) ucsf.edu
I was raised in Florida, where I completed my undergraduate education at FSU. I received my PhD from the University of Colorado Anschutz, where I characterized novel inhibitors of CHD1L and the PARP1-HPF1 complex. In the Gordan lab, I am working to target oncogenic signaling of PKA, as well as develop small molecule activators of LKB1. When I am not in the lab, you will likely find me rock climbing or playing the piano.
Weicheng Li, PhD
Postdoctoral Research Fellow
weicheng.li (at) ucsf.edu
bio coming soon
Huat Lim, MD
Assistant Professor
huatchye.lim (at) ucsf.edu
My work in the Gordan lab involves using computational genomics techniques to investigate the pathophysiology of hepatocellular carcinoma associated with hepatitis B virus infection. Outside the lab, I’m a hematology/oncology fellow at UCSF, where I also completed internal medicine residency. Before moving to San Francisco, I attended medical school at the University of Washington, and prior to that I worked as a software engineer and product manager at Amazon and Microsoft. When not working, you can often find me chasing my highly energetic young children around.
Kasturi Nayak, PhD
Associate Specialist
kasturi.nayak (at) ucsf.edu
I was born and raised in India, and completed my PhD work at Institute of Life Sciences Bhubaneswar, India. Before moving to UCSF, I worked as a post-doctoral fellow at SUNY, Buffalo where I have studied the role of SOX15 in head & neck squamous cell carcinoma. My work in the Gordal Lab will focus on developing small inhibitors targeting KRAS/MAPK pathway in colon cancer. Outside the lab I love to travel and explore new places. I also like to watch sports like tennis & cricket.
Clarise Rivera
Junior Specialist
I was raised in the Bay Area/Wine Country and graduated from the University of California, Berkeley with a BA in Biochemistry, Biophysics, and Structural Biology. As an undergraduate, I studied the dependency of Heat Shock Protein 90 (Hsp90) in regulating protein-folding stability of Src-family Kinases in John Kuriyan’s lab at both UC Berkeley and Vanderbilt University. Now, as a Junior Specialist in the Gordan Lab, I am super excited to branch my research into understanding Hsp70/Hsp90 linking adaptor protein, STIP1, and its impact on stability, activity, and mobility of mutant Protein Kinase A (PKA) in rare cancers. Apart from my research, I enjoy going to the gym, playing the violin, and going on hikes.
clarise.rivera (at) ucsf.edu
Rigney Turnham, PhD
Specialist
rigney.turnham (at) ucsf.edu
I was raised in New Mexico and attended university at NMSU. I then obtained my PhD in 2018 at the University of Washington in the laboratory of John D. Scott, where I studied fibrolamellar carcinoma and the oncogenic signaling of the fusion kinase, DNAJ-PKAc. In the Gordan lab, I am studying a variety of oncogenic and tumor suppressive signaling mechanisms and supporting projects in fibrolamellar, hepatocellular, and colorectal carcinoma. Additionally, I am also interested in identifying genomic markers of response and resistance to therapy in cholangiocarcinoma, and modeling their effects in vitro. In my free time, I like to run and bike around San Francisco.
Lab Alumni
Name | Previous Positions/Years | Next/Currently |
Lin Song-Kretschmer | Postdoctoral Scholar, 2023-2025 | Manager, Porton Pharma |
Verima Pereira | Postdoctoral Scholar, 2022-2025 | Research Scientist, Huang Lab |
Ananya Singh | Undergraduate Researcher, 2024-2025 | Junior Specialist, Guna Lab |
Bryan Pascual | Staff Research Associate, 2022-2024 |
|
Alex Yoon | Undergraduate Researcher, 2023 | UCSB |
Sally Ume-Ukeje | Intern, 2022, 2023, 2024 | Columbia |
Jolie Bilodeau | Intern, 2023, 2024 | Northeastern University |
Ayton Marzal | Intern, 2022 | UC Davis |
Gary Chan | Staff Research Associate 2018-2022 | PhD student, UCSF BMS |
LeeAnn Wang | Staff Research Associate, 2019-2022 | Emergency Medical Technician |
Dom Mitchell | Staff Research Associate, 2017-2021 | Clinical Research Coordinator, Stanford |
Yeonjoo (Christina) Hwang | Staff Research Associate, 2017-2021 | Masters Student, Georgetown |
Lucille Ferret | Master’s Student, 2021 | Graduate Student, Paris Saclay (Kroemer Lab) |
Katie Lo | Intern, 2021 | Medical Student, New York Medical College |
Alex Choi | Staff Research Associate/Lab Manager, 2015-2020 | Lab Manager, Varian |
Zoey Cao | Pumas Intern/Undergrad Thesis, 2019-2020 | Research Associate, Unity Biotechnology |
Lisie Thayer | Staff Research Associate, 2018-2019 | Analytics Manager, Upwave |
Katie Gutierrez | Intern, 2018 | Medical Student, UCSF/UCB joint program |