The Gordan Lab is an interdisciplinary research group based in the Quantitative Biosciences Institute (QBI) at UCSF. Our research focuses on basic and translational questions in the treatment of liver cancers, combining innovative proteomic methods with unique patient-derived models to identify new therapeutic targets and markers of drug response. We have three major areas of investigation:
1. Characterizing the impact of hepatitis viruses on liver cancer behavior and response to treatment
2. Developing small molecule strategies to target Hippo pathway dysregulation
3. Mapping oncogenic kinase signaling and its response to targeted therapeutics